Help on details
In the details page you need to choose the markers to include in the panel and determine the grouping variable.
The biomarkers you want to be included in the panel. There are two kinds of them: test or fixed.
Test markers will be tested for inclusion in the panel. They will be included only if they improve the classification. The downside is that the inclusion of more test markers will slow down the computation.
Select âFixed markersâ if you know they will improve the classification or if you want to include them anyway. Fixed markers will always be included in the panel, even if they worsen the classification.
The grouping variable determines the two groups that will be discriminated by the markers. A typical example of grouping variable is the âdiagnosisâ variable. Other example include âoutcomeâ, âgold standardâ or âpatient statusâ.
Typically, a grouping variable will have only a few possible values which you will then need to select as control (negative) or case (positive).